Tricyclic Antidepressants

《英文msh詞典》Tricyclic Antidepressants
[入口詞] Tricyclic Antidepressants
[主題詞] Antidepressive Agents,Tricyclic
[中文釋義] 三環抗抑郁劑
[英文釋義] Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin,adrenergic,and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.